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cenobamate will decrease the extent or impact of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Raise dose of CYP3A4 substrate, as needed, when coadministered with cenobamate.belzutifan will minimize the level or effect of fentanyl transdermal by influencing hepatic/intestinal